We have identified several issues that can be the origin of a highly priced medicine. Please find an overview of all issues below.
| Access problems due to monopoly |
| * Patent or IP legislation |
| * Supplementary protection certificates |
| * Data exclusivity |
| * Orphan market exclusivity |
| * Only one product registered |
| * No generic or therapeutic competition |
| * Supply chain issues |
| * API monopoly |
| Access problems due to high prices |
| * High prices due to monopoly |
| * High prices not due to monoply |
| * High production costs |
| * High ingredient costs |
| Access problems due to other barriers |
| * Weak health system |
| * Weak distribution system |
| * Registration barriers |
| * Financing or insurance barriers |